Impaired antibody responses and loss of reactivity to Onchocerca volvulus antigens by HIV-seropositive onchocerciasis patients.

@article{Tawill1996ImpairedAR,
  title={Impaired antibody responses and loss of reactivity to Onchocerca volvulus antigens by HIV-seropositive onchocerciasis patients.},
  author={Sallah Tawill and Michaela Gallin and Klaus D. Erttmann and Walter Eigen Kipp and Jotham Bamuhiiga and Dietrich W. B{\"u}ttner},
  journal={Transactions of the Royal Society of Tropical Medicine and Hygiene},
  year={1996},
  volume={90 1},
  pages={85-9}
}
The impact of concomitant human immunodeficiency virus (HIV) infection on the antibody response of onchocerciasis patients to Onchocerca volvulus antigens (OvAg) was studied by Western blotting and enzyme linked immunosorbent assay (ELISA). Immunoglobulin G (IgG) antibodies in sera from 45 HIV-sero-positive O. volvulus microfilariae (mf) carriers (HIV+/Ov+) recognized significantly fewer distinct O. volvulus antigenic bands, and responded less frequently to all detected bands compared to sera… CONTINUE READING