Impaired antibody response to conjugated meningococcal serogroup C vaccine in asplenic patients


The purpose of this study was to determine the quantity and quality of antibodies against the meningococcal serogroup C (MenC) conjugated vaccine in asplenic patients. In 116 asplenic patients, antibody concentrations (IgG) were measured against meningococcal serogroup C before and after immunisation. Of MenC-specific IgG, both antibody avidity and… (More)
DOI: 10.1007/s10096-010-1129-2


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