Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats.

@article{Culley2004ImpairedAO,
  title={Impaired acquisition of spatial memory 2 weeks after isoflurane and isoflurane-nitrous oxide anesthesia in aged rats.},
  author={Deborah J. Culley and Mark G Baxter and Catherine A Crosby and Rustam Yukhananov and Gregory Crosby},
  journal={Anesthesia and analgesia},
  year={2004},
  volume={99 5},
  pages={1393-7; table of contents}
}
Aged rats are impaired on a spatial memory task for at least 24-48 h after isoflurane-nitrous oxide anesthesia. In this study, we tested how long the impairment lasts and investigated the role of nitrous oxide. Eighteen-month-old rats were randomized to anesthesia for 2 h with 1.2% isoflurane with or without 70% nitrous oxide or a control group (30% oxygen). Two weeks later, rats were tested daily for 14 days on a 12-arm radial maze. The number of correct choices to first error, total errors… CONTINUE READING

From This Paper

Topics from this paper.

Citations

Publications citing this paper.
Showing 1-10 of 89 extracted citations

Similar Papers

Loading similar papers…