Impaired Toll-like receptor 2 signalling in monocytes from 5-year-old allergic children.

@article{Amoudruz2009ImpairedTR,
  title={Impaired Toll-like receptor 2 signalling in monocytes from 5-year-old allergic children.},
  author={Petra Amoudruz and Ulrika Holmlund and Shanie Saghafian-Hedengren and Caroline Nilsson and Eva Sverremark-Ekstr{\"o}m},
  journal={Clinical and experimental immunology},
  year={2009},
  volume={155 3},
  pages={387-94}
}
The relative composition of the two major monocytic subsets CD14(+)CD16(-) and CD14(+)CD16(+) is altered in some allergic diseases. These two subsets display different patterns of Toll-like receptor levels, which could have implications for activation of innate immunity leading to reduced immunoglobulin E-specific adaptive immune responses. This study aimed… CONTINUE READING