Impaired T lymphocyte function increases tumorigenicity and decreases tumor latency in a mouse model of head and neck cancer.

Abstract

Squamous cell carcinoma of the head and neck (HNSCC) is the sixth most frequent cancer worldwide. SCC is the most common malignant tumor of the oral cavity with over 35,000 cases and 8,000 deaths reported in the United States each year. Previous case studies have reported increased incidence of HNSCC in patients on immunosuppressive therapy for organ… (More)

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