Impaired RPE survival on aged submacular human Bruch's membrane.

@article{Gullapalli2005ImpairedRS,
  title={Impaired RPE survival on aged submacular human Bruch's membrane.},
  author={Vamsi K Gullapalli and Ilene K. Sugino and Yancy Van Patten and Sumit Shah and Marco Attilio Zarbin},
  journal={Experimental eye research},
  year={2005},
  volume={80 2},
  pages={235-48}
}
Resurfacing of diseased or iatrogenically damaged Bruch's membrane with healthy retinal pigment epithelium (RPE) has been proposed as adjunctive treatment for age-related macular degeneration (AMD). The purpose of this study was to determine whether cultured fetal human RPE cells can attach and differentiate on aged submacular human Bruch's membrane. Bruch's membrane was debrided to expose native RPE basement membrane, the superficial inner collagenous layer directly below the RPE basement… CONTINUE READING
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