Impaired Function of CD4+ T Follicular Helper (Tfh) Cells Associated with Hepatocellular Carcinoma Progression

@inproceedings{Jia2015ImpairedFO,
  title={Impaired Function of CD4+ T Follicular Helper (Tfh) Cells Associated with Hepatocellular Carcinoma Progression},
  author={Yiqiong Jia and Zhen Zeng and Yuanyuan Li and Zhiwei Li and Lei Jin and Zheng Zhang and Lifeng Wang and Fu-sheng Wang},
  booktitle={PloS one},
  year={2015}
}
BACKGROUND AND AIMS CD4+ T follicular helper (Tfh) cells, a new subset of immune cells, have been demonstrated to be involved in the development and prognosis of tumors. However, their functional role in human hepatocellular carcinoma (HCC) is relatively unknown, and the detailed mechanisms in HCC development remain to be described. METHODS A total of 85 HCC patients with hepatitis B virus (HBV) infection, 25 HBV-relative liver cirrhosis (LC) patients, and 20 healthy controls (HC) were… CONTINUE READING

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