Impaired Detoxication of Hydrogen Sulfide in Ulcerative Colitis?

@article{Picton2006ImpairedDO,
  title={Impaired Detoxication of Hydrogen Sulfide in Ulcerative Colitis?},
  author={R. Picton and M. Eggo and M. Langman and S. Singh},
  journal={Digestive Diseases and Sciences},
  year={2006},
  volume={52},
  pages={373-378}
}
Impaired butyrate oxidation and raised counts of sulfate-reducing bacteria in the colon of patients with ulcerative colitis (UC) indicate that the disease may be induced or aggravated by hydrogen sulfide toxicity. We aimed to examine enzymatic removal of H2S in erythrocytes and colonic mucosa from controls and patients with UC and Crohn's disease (CD). Rhodanese (RHOD) and thiol methyltransferase (TMT) activities were measured in rectal mucosa and erythrocytes, and plasma thiocyanate was… Expand
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