Impacts of the Mitochondrial Genome on the Relationship of Long-Term Ambient Fine Particle Exposure with Blood DNA Methylation Age.

@article{NwanajiEnwerem2017ImpactsOT,
  title={Impacts of the Mitochondrial Genome on the Relationship of Long-Term Ambient Fine Particle Exposure with Blood DNA Methylation Age.},
  author={Jamaji C. Nwanaji-Enwerem and Elena Colicino and Lingzhen Dai and Akin Cayir and Marco S{\'a}nchez-Guerra and Hannah E Laue and Vy Thuy Nguyen and Qian Di and Allan C. Just and Lifang Hou and Pantel Vokonas and Brent A. Coull and Marc G. Weisskopf and Andrea A. Baccarelli and Joel Schwartz},
  journal={Environmental science & technology},
  year={2017},
  volume={51 14},
  pages={
          8185-8195
        }
}
The mitochondrial genome has long been implicated in age-related disease, but no studies have examined its role in the relationship of long-term fine particle (PM2.5) exposure and DNA methylation age (DNAm-age)-a novel measure of biological age. In this analysis based on 940 observations between 2000 and 2011 from 552 Normative Aging Study participants, we determined the roles of mitochondrial DNA haplogroup variation and mitochondrial genome abundance in the relationship of PM2.5 with DNAm-age… CONTINUE READING
3
Twitter Mentions

Figures, Tables, and Topics from this paper.

Explore Further: Topics Discussed in This Paper

References

Publications referenced by this paper.
SHOWING 1-10 OF 67 REFERENCES