Impact of weight loss induced by gastric bypass or caloric restriction on oxidative stress and genomic damage in obese Zucker rats.

@article{Bankoglu2016ImpactOW,
  title={Impact of weight loss induced by gastric bypass or caloric restriction on oxidative stress and genomic damage in obese Zucker rats.},
  author={Ezgi Eyluel Bankoglu and Florian Seyfried and Laura Rotzinger and Arno Nordbeck and Caroline Corteville and Christian Jurowich and Christoph Thomas Germer and Christoph Otto and Helga Stopper},
  journal={Free radical biology & medicine},
  year={2016},
  volume={94},
  pages={208-17}
}
BACKGROUND Evidence on bariatric surgery induced weight loss and its possible impact on cancer risk is limited, but also controversial. We used obese Zucker(fa/fa) and lean Zucker(fa/+) to investigate the association between obesity, oxidative stress and genomic damage after weight loss induced either by Roux-en-Y gastric bypass surgery (RYGB) or caloric restriction. METHODS Male Zucker(fa/fa) rats underwent RYGB (n=15) or sham surgery (n=17). Five shams were food restricted and body weight… CONTINUE READING
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