Impact of virologic breakthrough and HBIG regimen on hepatitis B recurrence after liver transplantation.

@article{Degertekin2010ImpactOV,
  title={Impact of virologic breakthrough and HBIG regimen on hepatitis B recurrence after liver transplantation.},
  author={Bulent Degertekin and S H Han and Emmet B. Keeffe and Eugene R Schiff and Velimir A.C. Luketic and Robert S Brown and Sukru H. Emre and Consuelo Soldevila-Pico and K Rajender Reddy and Michael Brian Ishitani and Tram Anh T. Tran and Timothy L. Pruett and A S Lok},
  journal={American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons},
  year={2010},
  volume={10 8},
  pages={1823-33}
}
The availability of hepatitis B immune globulin (HBIG) and several oral antiviral therapies has reduced but not eliminated hepatitis B virus (HBV) recurrence. We aimed to determine the rate of HBV recurrence after orthotopic liver transplantation (OLT) in relation to virologic breakthrough pre-OLT and HBIG regimens post-OLT. Data from the NIH HBV-OLT database were analyzed. A total of 183 patients transplanted between 2001 and 2007 followed for a median of 42 months (range 1-81) post-OLT were… CONTINUE READING

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