Impact of viral and host DNA methylations on HPV16-related cervical cancer pathogenesis.

Abstract

Epigenetic alterations within human papillomavirus (HPV) and host cellular genomes are known to occur during cervical carcinogenesis. Our objective was to analyse the influence of (1) methylation within two immunostimulatory CpG motifs within HPV16 E6 and E7 genes around the viral late promoter and their correlation, if any, with expression deregulation of… (More)
DOI: 10.1177/1010428317699799

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