Impact of vagus nerve stimulation on sleep-related breathing disorders in adults with epilepsy

@article{Salvad2018ImpactOV,
  title={Impact of vagus nerve stimulation on sleep-related breathing disorders in adults with epilepsy},
  author={Aude Salvad{\'e} and Philippe Ryvlin and Andrea O. Rossetti},
  journal={Epilepsy \& Behavior},
  year={2018},
  volume={79},
  pages={126-129}
}

Tables from this paper

Anesthetic Management of a Patient With a Vagal Nerve Stimulator.

The successful anesthetic management of a 28-year-old woman with a VNS device who underwent dental treatment under general anesthesia, who was morbidly obese and had undergone placement of a V NS device secondary to drug-resistant epilepsy 2 years prior.

Vagus nerve stimulation (VNS) therapy update

Sleep Disorders in Epilepsy: Current Trends and Future Perspectives

Screening for and treating sleep disorders may lead to improved seizure control and quality of life in PWE, andEpilepsy surgery and implanted devices to treat refractory epilepsy provide new insights into the relationship between sleep and epilepsy.

Neuromodulation for Refractory Epilepsy

Three neuromodulation therapies, all using implanted device and electrodes, have been approved to treat adults with drug-resistant focal epilepsy, namely, the vagus nerve stimulation in 1995, deep

Neuromodulation in drug‐resistant epilepsy: A review of current knowledge

Although promising outcomes in adults and children with DRE have been achieved, challenges such as heterogeneity among epilepsy types and etiologies, optimization of stimulation parameters, a lack of biomarkers to predict response to neuromodulation therapies, high‐level evidence to aid decision‐making, and direct comparisons between neurommodulatory approaches remain remain.

Transcutaneous Vagus Nerve Stimulation Could Improve the Effective Rate on the Quality of Sleep in the Treatment of Primary Insomnia: A Randomized Control Trial

T-VNS appeared to be a safe and effective treatment for primary insomnia and no statistical differences in changes of HAMA and HAMD scores were detected between the two groups.

Research advances in the application of vagus nerve electrical stimulation in ischemic stroke

The current status of the application of VNS (invasive and non-invasive) in diverse functional impairments after an ischemic stroke is outlined, followed by an in-depth discussion of the underlying mechanisms of its mediated neuroprotective effects.

The Interface Between Sleep and Epilepsy

The role sleep plays in epilepsy and the importance for evaluating and treating sleep issues in patients with epilepsy are highlighted and new insights to the possible mechanisms contributing to the development of resistant epilepsies are offered.

References

SHOWING 1-10 OF 37 REFERENCES

Effects of vagus nerve stimulation on respiration during sleep

VNS is associated with adverse changes in respiration during sleep and in patients with preexisting OSA, VNS should be administered with care, and lowering stimulus frequency, but not stimulus intensity, pulse width, or on-time, ameliorated VNS-related apneas and hypopneas.

Laryngeal motility alteration: A missing link between sleep apnea and vagus nerve stimulation for epilepsy

The association between VNS‐induced LVCA and SBD was statistically significant and supports the need to routinely investigate sleep respiratory and laryngeal motility patterns before and after VNS implantation.

Respiratory Pattern Changes in Sleep in Children on Vagal Nerve Stimulation for Refractory Epilepsy

The results suggest that RPCS occur in most children with VNS, not surprising in view of the significant influence vagal afferents have on respiratory control centres.

The therapeutic dilemma of vagus nerve stimulator-induced sleep disordered breathing

With decrease in VNS output current, patient's SDB improved, but seizure activity exacerbated, which required a return to the original settings, illustrating the need for clinicians to balance seizure control and SDB in patients with VNS.

Vagus nerve stimulation in children with refractory epilepsy: unusual complications and relationship to sleep-disordered breathing

VNS appears to be an effective treatment for children with refractory epilepsy, with development of intractable cough in one patient in spite of device being turned off and recurrent infection-related removal in another are unusual complications.

Vagus nerve stimulation reduces daytime sleepiness in epilepsy patients

Treatment with VNS at low stimulus intensities improves daytime sleepiness, even in subjects without reductions in seizure frequency, which supports the role of VNS in activating cholinergic and other brain regions that promote alertness.

Sleep-related breathing disorder in children with vagal nerve stimulators.

Treatment of Refractory Partial Seizures: Preliminary Results of a Controlled Study

It is demonstrated that vagus nerve stimulation is a safe and effective method of treating partial epileptic seizures and ratings of the patient's overall condition, the patient, investigator, and companion as a measurement of “quality of life” also show improvement in the HIGH group.