Impact of unreported HIV-1 reverse transcriptase mutations on phenotypic resistance to nucleoside and non-nucleoside inhibitors.

@article{Saracino2006ImpactOU,
  title={Impact of unreported HIV-1 reverse transcriptase mutations on phenotypic resistance to nucleoside and non-nucleoside inhibitors.},
  author={Annalisa Saracino and Laura Monno and Luigia Scudeller and Donatella Concetta Cibelli and Alessandra Tartaglia and Grazia Punzi and Carlo Torti and Sergio lo Caputo and Francesco Mazzotta and Gaetano Scotto and Giampiero Carosi and Gioacchino Angarano},
  journal={Journal of medical virology},
  year={2006},
  volume={78 1},
  pages={9-17}
}
An extended spectrum of HIV-1 reverse-transcriptase (RT) mutations in HAART-treated patients has been recently described. To verify the possible association of previously unreported RT mutations with a decrease of phenotypic susceptibility to nucleoside (NRTIs) and non-nucleoside (NNRTIs) RT inhibitors, the RT sequence of 328 HIV-1-positive patients (102 naïve and 226 treated with HAART participating in either the PhenGen or Genpherex study) was analyzed. All treated patients were tested at the… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 19 extracted citations

Similar Papers

Loading similar papers…