Impact of trimethoprim-sulfamethoxazole prophylaxis on falciparum malaria infection and disease.

@article{Thera2005ImpactOT,
  title={Impact of trimethoprim-sulfamethoxazole prophylaxis on falciparum malaria infection and disease.},
  author={Mahamadou A Thera and Paul S Sehdev and D. Coulibaly and Karim Traore and Mamane N Garba and Yacouba Cissoko and Abdoulaye Kassoum Kone and Ando B. Guindo and Alassane Dicko and Abdoul Habib Beavogui and Abdoulaye A. Djimd{\'e} and Kirsten E. Lyke and Dapa Aly Diallo and Ogobara K. Doumbo and Christopher V. Plowe},
  journal={The Journal of infectious diseases},
  year={2005},
  volume={192 10},
  pages={1823-9}
}
BACKGROUND Trimethoprim-sulfamethoxazole (TS) prophylaxis is recommended for persons living with human immunodeficiency virus infection and acquired immunodeficiency syndrome in Africa. TS and the antimalarial combination sulfadoxine-pyrimethamine (SP) share mechanisms of action and resistance patterns, and concerns about the impact of TS resistance on SP efficacy have contributed to reluctance to implement TS prophylaxis in Africa. METHODS To determine whether TS prophylaxis impairs SP… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 64 extracted citations

Similar Papers

Loading similar papers…