Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials.

@article{Andes2012ImpactOT,
  title={Impact of treatment strategy on outcomes in patients with candidemia and other forms of invasive candidiasis: a patient-level quantitative review of randomized trials.},
  author={David R Andes and Nasia Safdar and John W. Baddley and Geoffrey Playford and Annette C. Reboli and John Rex and Jack D. Sobel and Peter G. Pappas and Bart Jan Kullberg},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2012},
  volume={54 8},
  pages={
          1110-22
        }
}
BACKGROUND Invasive candidiasis (IC) is an important healthcare-related infection, with increasing incidence and a crude mortality exceeding 50%. Numerous treatment options are available yet comparative studies have not identified optimal therapy. METHODS We conducted an individual patient-level quantitative review of randomized trials for treatment of IC and to assess the impact of host-, organism-, and treatment-related factors on mortality and clinical cure. Studies were identified by… CONTINUE READING
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