Impact of transposable elements on the evolution of mammalian gene regulation

  title={Impact of transposable elements on the evolution of mammalian gene regulation},
  author={Patrik Medstrand and Louie N. van de Lagemaat and Catherine A Dunn and Josette Ren{\'e}e Landry and Daniel Svenback and Dixie L. Mager},
  journal={Cytogenetic and Genome Research},
  pages={342 - 352}
Transposable elements (TEs) are present in all organisms and nearly half of the human and mouse genome is derived from ancient transpositions. This fact alone suggests that TEs have played a major role in genome organization and evolution. Studies undertaken over the last two decades or so clearly show that TEs of various kinds have played an important role in organism evolution. Here we review the impact TEs have on the evolution of gene regulation and gene function with an emphasis on humans… 

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