Impact of transmitted drug-resistance on treatment selection and outcome of first-line Highly Active Antiretroviral Therapy (HAART).

@article{Bansi2010ImpactOT,
  title={Impact of transmitted drug-resistance on treatment selection and outcome of first-line Highly Active Antiretroviral Therapy (HAART).},
  author={Loveleen K Bansi and Anna Mar{\'i}a Geretti and David Dunn and Teresa A. Garrett Hill and Hannah Green and Esther Fearnhill and Brian Gazzard and Mark Nelson and Kholoud Porter and Andrew Phillips and Caroline Sabin},
  journal={Journal of acquired immune deficiency syndromes},
  year={2010},
  volume={53 5},
  pages={633-9}
}
OBJECTIVE The study aim was to determine how resistance testing influences outcome of first-line highly active antiretroviral therapy (HAART) in routine practice in the United Kingdom. METHODS The prevalence of transmitted drug resistance and the genotypic sensitivity score (GSS) of first-line HAART regimens were determined using data from the UK Collaborative HIV Cohort(CHIC) Study. Factors associated with starting a regimen with a reduced GSS and subsequent virological responses were… CONTINUE READING

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