Impact of thorough block sampling in the histologic evaluation of melanomas.

  title={Impact of thorough block sampling in the histologic evaluation of melanomas.},
  author={Senait W Dyson and Jonathan L Bass and Jerome Pomeranz and Christine Jaworsky and Jessica E Sigel and Stephen C. Somach},
  journal={Archives of dermatology},
  volume={141 6},
OBJECTIVE To determine if changes in histologic parameters obtained from intermittent sampling of the entire block correlated with differences in prognosis and management. DESIGN Prospective analysis of skin biopsy specimens. SETTING Skin pathology laboratory. Patients One hundred consecutive patients with an unequivocal diagnosis of melanoma. Interventions Two initial slides were prepared from serial sections of 5-mum thickness. When evaluation of the initial slide revealed melanoma, 5… CONTINUE READING
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Diagnosis and treatment of early melanoma

  • N Cascinelli, EP vanderEsch, A Morabito
  • JAMA
  • 1992

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