Impact of the variability of cyclosporin A trough levels on long-term renal allograft function.

@article{Waiser2002ImpactOT,
  title={Impact of the variability of cyclosporin A trough levels on long-term renal allograft function.},
  author={Johannes Waiser and Torsten Slowinski and Andrea Brinker-Paschke and Klemens Budde and Matthias Schreiber and Torsten Boehler and Ingeborg Hauser and H N Neumayer},
  journal={Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association},
  year={2002},
  volume={17 7},
  pages={1310-7}
}
BACKGROUND Among renal allograft recipients, there is a considerable variability in cyclosporin A (CsA) trough levels. Some of the CsA metabolites are pharmacologically active. The variability of polyclonal CsA trough levels may contribute to the fact that long-term renal allograft survival is still not satisfactory. In a retrospective, single-centre study, we investigated the influence of the variability of polyclonal CsA trough levels on long-term renal allograft function. METHODS Patients… CONTINUE READING

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