Impact of the high-affinity proline permease gene (putP) on the virulence of Staphylococcus aureus in experimental endocarditis.

@article{Bayer1999ImpactOT,
  title={Impact of the high-affinity proline permease gene (putP) on the virulence of Staphylococcus aureus in experimental endocarditis.},
  author={Arnold S. Bayer and Silvija N. Coulter and C. Kendal Stover and William R Schwan},
  journal={Infection and immunity},
  year={1999},
  volume={67 2},
  pages={740-4}
}
Staphylococcus aureus causes a wide variety of invasive human infections. However, delineation of the genes which are essential for the in vivo survival of this pathogen has not been accomplished to date. Using signature tag mutagenesis techniques and large mutant pool screens, previous investigators identified several major gene classes as candidate… CONTINUE READING