Impact of the fluoroquinolones on gastrointestinal flora.

@article{Korten1989ImpactOT,
  title={Impact of the fluoroquinolones on gastrointestinal flora.},
  author={Volkan Korten and Barbara E. Murray},
  journal={Drugs},
  year={1989},
  volume={45 Suppl 3},
  pages={
          125-33
        }
}
A number of studies have been performed to evaluate the effect of the fluoroquinolones on gastrointestinal flora. The fluoroquinolones have only slight or no effect on the oropharyngeal flora, except when Neisseria, Haemophilus or Branhamella spp. are present. Studies have consistently shown that Gram-negative facultative bacteria of the lower intestinal flora are strongly suppressed during administration of these agents. Total faecal anaerobes are generally unchanged. The effect of the… CONTINUE READING