Impact of the epoxide hydrolase EphD on the metabolism of mycolic acids in mycobacteria.

Abstract

Mycolic acids are the hallmark of the cell envelope in mycobacteria, which include the important human pathogens Mycobacterium tuberculosis and Mycobacterium leprae Mycolic acids are very long C60-C90 α-alkyl β-hydroxy fatty acids having a variety of functional groups on their hydrocarbon chain that define several mycolate types. Mycobacteria also produce… (More)
DOI: 10.1074/jbc.RA117.000246

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