Impact of the agr quorum-sensing system on adherence to polystyrene in Staphylococcus aureus.

@article{Vuong2000ImpactOT,
  title={Impact of the agr quorum-sensing system on adherence to polystyrene in Staphylococcus aureus.},
  author={Cuong Vuong and Henri L. Saenz and Friedrich G{\"o}tz and Michael Otto},
  journal={The Journal of infectious diseases},
  year={2000},
  volume={182 6},
  pages={1688-93}
}
Biofilm formation by Staphylococcus aureus is a serious problem in nosocomial infections. There are great differences in the capacity of S. aureus to express biofilms, but the reasons are unknown. In all, 105 S. aureus strains were tested for a correlation between the agr quorum-sensing system phenotype and the ability of S. aureus to adhere to polystyrene. Some 78% of agr-negative, but only 6% of agr-positive, strains formed a biofilm, demonstrating a profound impact of agr on biofilm… CONTINUE READING

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