Impact of the Cellular Prion Protein on Amyloid-and 3 PO-Tau Processing

  • Matthias Schmitza, Katharina Wulfa, +6 authors Inga Zerra
  • Published 2013

Abstract

Previous studies indicate an important role for the cellular prion protein (PrPC) in the development of Alzheimer’s disease (AD) pathology. In the present study, we analyzed the involvement of PrPC in different pathological mechanisms underlying AD: the processing of the amyloidprotein precursor (A PP) and its interaction with A PP, tau, and different… (More)

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