Impact of taurolidine on the growth of CC531 coloncarcinoma cells in vitro and in a laparoscopic animal model in rats

@article{Nestler2003ImpactOT,
  title={Impact of taurolidine on the growth of CC531 coloncarcinoma cells in vitro and in a laparoscopic animal model in rats},
  author={Gerd Nestler and H. U. Schulz and Daniel Schubert and Sabine Krueger and Hans Lippert and Matthias Pross},
  journal={Surgical Endoscopy And Other Interventional Techniques},
  year={2003},
  volume={19},
  pages={280-284}
}
The object of this study was to examine the effect of taurolidine on intraabdominal tumor growth in a laparoscopic animal model. We tested the cytotoxic, antiadhesive, and anti-invasive effects of this substance on CC531 adenocarcinoma cells in vitro and in vivo using WAG rats. For in vitro experiments, Transwell dual chambers with polycarbonate filters coated with 100 μg/cm2 Matrigel were used to investigate the effects of 5, 10, and 20 μl of 2.0% taurolidine on the invasion of 1 × 105 CC531… CONTINUE READING

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Current attitudes in laparoscopic colorectal surgery

Surgical Endoscopy And Other Interventional Techniques • 2002
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