Impact of surgical trauma on human skeletal muscle protein synthesis.

  title={Impact of surgical trauma on human skeletal muscle protein synthesis.},
  author={Inga Tj{\"a}der and Pia Ess{\'e}n and Peter J. Garlick and Margaret A McMnurlan and Olav Rooyackers and J Wernerman},
  journal={Clinical science},
  volume={107 6},
Muscle protein catabolism is a considerable clinical problem following surgery. However, the impact of surgical trauma on muscle protein synthesis is not well characterized. In this pilot study, we therefore investigated whether the severity of surgical trauma is related to a decrease in muscle protein synthesis rate in humans. Metabolically healthy patients (n=28) were included in the study. Eight of the patients were day-care patients undergoing minor breast surgery (defined as minor surgery… CONTINUE READING


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