Impact of sleep debt on metabolic and endocrine function
@article{Spiegel1999ImpactOS, title={Impact of sleep debt on metabolic and endocrine function}, author={K. Spiegel and R. Leproult and E. Cauter}, journal={The Lancet}, year={1999}, volume={354}, pages={1435-1439} }
BACKGROUND
Chronic sleep debt is becoming increasingly common and affects millions of people in more-developed countries. [...] Key MethodMETHODS
We assessed carbohydrate metabolism, thyrotropic function, activity of the hypothalamo-pituitary-adrenal axis, and sympathovagal balance in 11 young men after time in bed had been restricted to 4 h per night for 6 nights.Expand
Paper Mentions
Interventional Clinical Trial
Women with a history of gestational diabetes (GDM) are at high risk of developing diabetes in
the future. Sleep disturbances are emerging as risk factors for incident diabetes. The… Expand
Conditions | Gestational Diabetes |
---|---|
Intervention | Behavioral |
Interventional Clinical Trial
The overall goal of this project is to test the hypothesis that long-term, sustained sleep
restriction (SR), in women, will lead to increased cardio-metabolic risk. This will be… Expand
Conditions | Cardiovascular Disease, Obesity, Sleep |
---|---|
Intervention | Other |
News Article
Interventional Clinical Trial
The purpose of this study is to compare cardiovascular physiological adaptation to
intermittent hypoxia (IH) of nonobese healthy subjects. The exposure will be two periods of
two… Expand
Conditions | Hypoxia, Obstructive Sleep Apnea, Sleep Apnea |
---|---|
Intervention | Drug |
3,029 Citations
Sleep as a Mediator of the Relationship between Socioeconomic Status and Health: A Hypothesis
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Partial sleep restriction modulates secretory activity of thyrotropic axis in healthy men
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Sleep loss alters basal metabolic hormone secretion and modulates the dynamic counterregulatory response to hypoglycemia.
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Adverse effects of two nights of sleep restriction on the hypothalamic-pituitary-adrenal axis in healthy men.
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Adverse effects of modest sleep restriction on sleepiness, performance, and inflammatory cytokines.
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Timing Modulates the Effect of Sleep Loss on Glucose Homeostasis.
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