Impact of sepsis on the urinary level of interleukin-18 and cystatin C in critically ill neonates

@article{Li2012ImpactOS,
  title={Impact of sepsis on the urinary level of interleukin-18 and cystatin C in critically ill neonates},
  author={Yanhong Li and Xiaozhong Li and Xiaofei Zhou and Jie Yan and Xueping Zhu and Jian Pan and Meifang Jin and Xueming Zhu and Xing Feng and Zhihui Xiao},
  journal={Pediatric Nephrology},
  year={2012},
  volume={28},
  pages={135-144}
}
Urinary interleukin-18 (uIL-18) and cystatin C (uCysC) are biomarkers of acute kidney injury (AKI). We hypothesized that in non-AKI neonates, the level of uIL-18 and uCysC would be higher in those with sepsis compared to those without sepsis. The aims of this study were to determine the association between urinary biomarkers and sepsis in non-AKI critically ill neonates, and to evaluate whether uIL-18 and uCysC could serve as predictors of sepsis in this population. The study included 111 non… CONTINUE READING
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