Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders.

@article{Elisei2004ImpactOR,
  title={Impact of routine measurement of serum calcitonin on the diagnosis and outcome of medullary thyroid cancer: experience in 10,864 patients with nodular thyroid disorders.},
  author={Rossella Elisei and Valeria Bottici and Fabiana Luchetti and Giancarlo Di Coscio and Cristina Romei and Lucia Grasso and Paolo Miccoli and Pietro Iacconi and Fulvio Basolo and Aldo Pinchera and F. Rossi Pacini},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2004},
  volume={89 1},
  pages={163-8}
}
The survival rate of patients with medullary thyroid carcinoma (MTC) is significantly better in patients diagnosed and treated when the tumor is limited to the thyroid. In a pioneer study carried out in 1991, we demonstrated that routine measurement of serum calcitonin (CT) in nodular thyroid disease allowed the preoperative diagnosis of unsuspected sporadic MTC with better accuracy than routine fine needle aspiration cytology (FNAC). This finding has been confirmed in subsequent studies. In… CONTINUE READING

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