Impact of response to chemotherapy and treating institution on survival in primary CNS lymphoma (PCNSL): Long-term results of the multicenter BMPD study.

@article{Korfel2004ImpactOR,
  title={Impact of response to chemotherapy and treating institution on survival in primary CNS lymphoma (PCNSL): Long-term results of the multicenter BMPD study.},
  author={Agnieszka Korfel and Peter Martus and Mohammad Resa Nowrousian and Dieter Kurt Hossfeld and Wolfgang Weber and Joachim Br{\"u}cher and Wolfgang E. Berdel and J Birkmann and Christian Peschel and Eckhard Thiel},
  journal={Journal of clinical oncology : official journal of the American Society of Clinical Oncology},
  year={2004},
  volume={22 14_suppl},
  pages={1522}
}
1522 Background: The role of adjuvant whole-brain irradiation (WBI) in PCNSL remains to be defined. Eliminating WBI from the initial treatment could reduce neurotoxicity but also adversly affect disease control and survival. METHODS Fifty-six patients were included in this prospective multicenter trial to evaluate the role of adjuvant WBI in PCNSL:. All received chemotherapy (CHX) composed of carmustine, high-dose methotrexate (HD-MTX) 1.5 g/m2, procarbazine, and dexamethasone (only in course… CONTINUE READING