Impact of repeated stressor exposure on the release of corticotropin-releasing hormone, arginine-vasopressin and bombesin-like peptides at the anterior pituitary

@article{Merali2009ImpactOR,
  title={Impact of repeated stressor exposure on the release of corticotropin-releasing hormone, arginine-vasopressin and bombesin-like peptides at the anterior pituitary},
  author={Zul Merali and Shawn P Hayley and Pam Kent and Judy F. McIntosh and Tania B{\'e}dard and Hymie Anisman},
  journal={Behavioural Brain Research},
  year={2009},
  volume={198},
  pages={105-112}
}
Repeated exposure to stressors was reported to increase the expression of arginine-vasopressin (AVP), especially in corticotropin-releasing hormone (CRH) neurons co-expressing AVP, within the hypothalamus. This may increase the potential for subsequent stressor-elicited enhancement of hypothalamic-pituitary-adrenal (HPA) functioning as these peptides synergistically stimulate pituitary ACTH secretion. Likewise, members of the bombesin (BB) family of peptides (including its mammalian analogues… Expand
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