Impact of repeated exposure on the toxicokinetics of BDE 47 in mice.

@article{Staskal2006ImpactOR,
  title={Impact of repeated exposure on the toxicokinetics of BDE 47 in mice.},
  author={Daniele F Staskal and Janet J. Diliberto and Linda S Birnbaum},
  journal={Toxicological sciences : an official journal of the Society of Toxicology},
  year={2006},
  volume={89 2},
  pages={380-5}
}
2,2',4,4'-Tetrabromodiphenyl ether (BDE 47) is the major polybrominated diphenyl ether (PBDE) found in environmental samples and human tissue despite its small contribution to global production and usage. Currently, three toxicokinetic studies are available investigating single-dose exposures; this is the first study to investigate toxicokinetic parameters following repeated exposure to BDE 47. The disposition and excretion of BDE 47 was monitored in adult female C57BL/6 mice for 5 days… CONTINUE READING

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