Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism.

@article{Laucht2009ImpactOP,
  title={Impact of psychosocial adversity on alcohol intake in young adults: moderation by the LL genotype of the serotonin transporter polymorphism.},
  author={Manfred Laucht and Jens Treutlein and Brigitte Schmid and Dorothea Blomeyer and Katja Becker and Arlette F. Buchmann and Martin H. Schmidt and Guenter Esser and Christine Jennen-Steinmetz and Marcella Rietschel and Ulrich S. Zimmermann and Tobias Banaschewski},
  journal={Biological psychiatry},
  year={2009},
  volume={66 2},
  pages={102-9}
}
BACKGROUND Evidence from animal studies supports a role for serotonin transporter gene promoter polymorphism (5-HTTLPR) gene-environment interaction (G x E) in the development of excessive alcohol intake. Few studies in humans have been conducted on this topic, yielding inconsistent results. The present study aims to further explore G x E between 5-HTTLPR and exposure to psychosocial adversity on alcohol consumption in a high-risk community sample of young adults. METHODS Data were collected… CONTINUE READING

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