Impact of prior irregular infliximab dosing on performance of long-term infliximab maintenance therapy in Crohn's disease.

@article{Stein2010ImpactOP,
  title={Impact of prior irregular infliximab dosing on performance of long-term infliximab maintenance therapy in Crohn's disease.},
  author={D. J. Stein and Ashwin N. Ananthakrishnan and Mazen Issa and John Barton Williams and Dawn B. Beaulieu and Yelena Zadvornova and Anita Ward and Kathryn Johnson and Josh F Knox and Sue Skaros and David G. Binion},
  journal={Inflammatory bowel diseases},
  year={2010},
  volume={16 7},
  pages={
          1173-9
        }
}
BACKGROUND Infliximab is efficacious in the management of moderate to severe Crohn's disease (CD). There are limited data regarding performance of infliximab in patients who require reinitiation of maintenance dosing following previous irregular exposure. METHODS This was a retrospective, observational study of CD patients treated with maintenance infliximab beyond 3 years. Maintenance infliximab infusion regimens were categorized as scheduled maintenance (SM) (maintenance infusions q < or =8… CONTINUE READING
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