Impact of primary molecular cytogenetic abnormalities and risk of progression in smoldering multiple myeloma

@article{Rajkumar2013ImpactOP,
  title={Impact of primary molecular cytogenetic abnormalities and risk of progression in smoldering multiple myeloma},
  author={S Vincent Rajkumar and Vinay Gupta and Rafael Fonseca and Angela Dispenzieri and Wilson I Gonsalves and Dirk Larson and Rhett P. Ketterling and John A. Lust and Robert A Kyle and Shaji K Kumar},
  journal={Leukemia},
  year={2013},
  volume={27},
  pages={1738-1744}
}
We studied 351 patients with smoldering multiple myeloma (SMM) in whom the underlying primary molecular cytogenetic subtype could be determined based on cytoplasmic immunoglobulin fluorescent in situ hybridization studies. Hundred and fifty-four patients (43.9%) had trisomies, 127 (36.2%) had immunoglobulin heavy chain (IgH) translocations, 14 (4%) both trisomies and IgH translocations, 53 (15.1%) no abnormalities detected and 3 (0.9%) had monosomy13/del(13q) in the absence of any other… CONTINUE READING
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References

Publications referenced by this paper.
Showing 1-10 of 44 references

Redefining myeloma

  • SV Rajkumar, G Merlini, JF SanMiguel
  • Nature Rev Clin Oncol
  • 2012

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