Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept.

@article{Ahlborg1992ImpactOP,
  title={Impact of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls on human and environmental health, with special emphasis on application of the toxic equivalency factor concept.},
  author={Ulf G. Ahlborg and Abraham A. Brouwer and Marilyn A. Fingerhut and Joseph L Jacobson and Sandra W. Jacobson and Scott W. Kennedy and Antonius A Kettrup and Jan Koeman and Hermann Poiger and Christoffer Rappe},
  journal={European journal of pharmacology},
  year={1992},
  volume={228 4},
  pages={179-99}
}
A scientific evaluation was made of the mechanisms of action of polychlorinated dibenzo-p-dioxins, dibenzofurans and biphenyls. Distinction is made between the aryl-hydrocarbon (Ah) receptor-mediated and non-Ah receptor-mediated toxic responses. Special attention is paid to the applicability of the toxic equivalency factor (TEF) concept. 

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