Impact of pneumoperitoneum on tumor growth

  title={Impact of pneumoperitoneum on tumor growth},
  author={Fabrice R L{\'e}curu and Aubert Agostini and Sophie Camatte and François Robin and Martine Aggerbeck and Jean Philippe Ja{\"i}s and Françoise Vild{\'e} and Roland Taurelle},
  journal={Surgical Endoscopy And Other Interventional Techniques},
Aim of the study: To compare intraperitoneal tumor growth after CO2 laparoscopy (L), gasless laparoscopy (GL), midline laparotomy (ML), and general anesthesia (GA) as a control. Materials and methods: A prospective randomized trial was carried out in nude rats. A carcinomatosis was obtained by intraperitoneal injection of either one of the two human ovarian cancer cell lines IGR-OV1 or NIH:OVCAR-3. Rats secondly underwent randomly different kind of procedures: CO2 L (8 mmHg, 60 min), GL… CONTINUE READING
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