Impact of persistent cortical activity (up States) on intracortical and thalamocortical synaptic inputs.

@article{Rigas2009ImpactOP,
  title={Impact of persistent cortical activity (up States) on intracortical and thalamocortical synaptic inputs.},
  author={Pavlos Rigas and Manuel A Castro-Alamancos},
  journal={Journal of neurophysiology},
  year={2009},
  volume={102 1},
  pages={119-31}
}
The neocortex generates short epochs of persistent activity called up states, which are associated with changes in cellular and network excitability. Using somatosensory thalamocortical slices, we studied the impact of persistent cortical activity during spontaneous up states on intrinsic cellular excitability (input resistance) and on excitatory synaptic inputs of cortical cells. At the intrinsic excitability level, we found that the expected decrease in input resistance (high conductance… CONTINUE READING
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