Impact of perinatal exposure to high-fat diet and stress on responses to nutritional challenges, food-motivated behaviour and mesolimbic dopamine function

@article{RomanPrez2017ImpactOP,
  title={Impact of perinatal exposure to high-fat diet and stress on responses to nutritional challenges, food-motivated behaviour and mesolimbic dopamine function},
  author={Marina Roman{\'i}-P{\'e}rez and Amandine L L{\'e}pinay and Leticia Espinosa Alonso and M Rincel and Liang Z. Xia and Herv{\'e} Fanet and Stephanie Caille and Martine Cador and Sophie Lay{\'e} and Sylvie Vancassel and Marie Darnaudery},
  journal={International Journal of Obesity},
  year={2017},
  volume={41},
  pages={502-509}
}
Background/Objectives:Energy-dense food exposure and stress during development have been suggested to contribute to obesity and metabolic disorders later in life. Although these factors are frequently associated, the effects of their combination have not yet been investigated. In this study, using an animal model, we examined the long-term impact of maternal high-fat diet (HFD) and early-life stress (ELS) on energy homoeostasis control and food motivation.Methods:Body weight growth under HFD… CONTINUE READING
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