Impact of parturition on chemokine homing factor expression in the vaginal distention model of stress urinary incontinence.

@article{Lenis2013ImpactOP,
  title={Impact of parturition on chemokine homing factor expression in the vaginal distention model of stress urinary incontinence.},
  author={Andrew T. Lenis and Mei Kuang and Lynn L. Woo and Adonis Z Hijaz and Marc S. Penn and Robert S. Butler and Raymond R. Rackley and Margot S. Damaser and Hadley M. Wood},
  journal={The Journal of urology},
  year={2013},
  volume={189 4},
  pages={1588-94}
}
PURPOSE Human childbirth simulated by vaginal distention is known to increase the expression of chemokines and receptors involved in stem cell homing and tissue repair. We hypothesized that pregnancy and parturition in rats contributes to the expression of chemokines and receptors after vaginal distention. MATERIALS AND METHODS We used 72 age matched female Lewis rats, including virgin rats with and without vaginal distention, and delivered rats with and without vaginal distention. Each rat… CONTINUE READING
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