Impact of osmolality on burning sensations during and immediately after intramuscular injection of 0.5 ml of vaccine suspensions in healthy adults.

@article{Nony2001ImpactOO,
  title={Impact of osmolality on burning sensations during and immediately after intramuscular injection of 0.5 ml of vaccine suspensions in healthy adults.},
  author={Patrice Nony and Pierre Girard and Sylvie Chabaud and Luc Hessel and Christophe Th{\'e}bault and Jean Pierre Boissel},
  journal={Vaccine},
  year={2001},
  volume={19 27},
  pages={3645-51}
}
A randomised placebo controlled double-blind cross-over trial was performed on twenty healthy adults to assess the effect of osmolality (300,600,850 and 1100 mOsm) on local tolerance of an intramuscular injection (0.5 ml) of five suspensions containing the same components as the excipients of a combined Diphtheria-Tetanus-acellular Pertussis-inactivated… CONTINUE READING