Impact of obsessive-compulsive disorder on the antimanic response to olanzapine therapy in youth with bipolar disorder.

@article{Joshi2010ImpactOO,
  title={Impact of obsessive-compulsive disorder on the antimanic response to olanzapine therapy in youth with bipolar disorder.},
  author={Gagan Joshi and Eric O. Mick and Janet Wozniak and Daniel S. Geller and Jennifer K Park and Samara Strauss and Joseph Biederman},
  journal={Bipolar disorders},
  year={2010},
  volume={12 2},
  pages={196-204}
}
OBJECTIVE To compare antimanic response to olanzapine therapy in youth with bipolar disorder (BPD) based on the status of comorbidity with obsessive-compulsive disorder (OCD). METHODS Secondary analysis of identically designed 8-week open-label trials of olanzapine therapy in youth with BPD. Severity of mania assessed with the Young Mania Rating Scale (YMRS) and Clinical Global Impression (CGI) scales. RESULTS Of the 52 BPD subjects (mean age 8.4 +/- 3.1 years) enrolled in the olanzapine… CONTINUE READING

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