Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk

@article{Sanghera2007ImpactON,
  title={Impact of nine common type 2 diabetes risk polymorphisms in Asian Indian Sikhs: PPARG2 (Pro12Ala), IGF2BP2, TCF7L2 and FTO variants confer a significant risk},
  author={Dharambir K Sanghera and Lyda Milena Olarte Ortega and Shizhong Han and Jairup Singh and Sarju K. Ralhan and Gurpreet Singh Wander and Narinder K Mehra and John J. Mulvihill and Robert E. Ferrell and Swapan K Nath and M. Kamboh},
  journal={BMC Medical Genetics},
  year={2007},
  volume={9},
  pages={59 - 59}
}
BackgroundRecent genome-wide association (GWA) studies have identified several unsuspected genes associated with type 2 diabetes (T2D) with previously unknown functions. In this investigation, we have examined the role of 9 most significant SNPs reported in GWA studies: [peroxisome proliferator-activated receptor gamma 2 (PPARG2; rs 1801282); insulin-like growth factor two binding protein 2 (IGF2BP2; rs 4402960); cyclin-dependent kinase 5, a regulatory subunit-associated protein1-like 1 (CDK5… CONTINUE READING
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