Impact of next generation sequencing on diagnostics in a genetic skin disease clinic.

@article{Takeichi2013ImpactON,
  title={Impact of next generation sequencing on diagnostics in a genetic skin disease clinic.},
  author={Takuya Takeichi and Arti Nanda and Lu Liu and A Salam and Patrick Campbell and Kenneth T Fong and Masashi Akiyama and Linda Ozoemena and Kristina L Stone and Hejab A. Al-Ajmi and Michael J. A. Simpson and J A McGrath},
  journal={Experimental dermatology},
  year={2013},
  volume={22 12},
  pages={825-31}
}
Individuals with inherited skin diseases often pose one of the most difficult diagnostic challenges in dermatology. The hunt for the underlying molecular pathology may involve candidate gene screening or linkage analysis, which is usually determined by the initial history, the physical findings and laboratory tests. Recent technical advances in DNA… CONTINUE READING