Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples.

@article{Nikiforov2011ImpactOM,
  title={Impact of mutational testing on the diagnosis and management of patients with cytologically indeterminate thyroid nodules: a prospective analysis of 1056 FNA samples.},
  author={Yuri E Nikiforov and N Paul Ohori and Steven P. Hodak and Sally E. Carty and Shane O Lebeau and Robert L Ferris and Linwah Yip and Raja R Seethala and Mitchell E. Tublin and Michael Stang and Christopher J. Coyne and Jonas T. Johnson and Andrew Francis Stewart and Marina N. Nikiforova},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2011},
  volume={96 11},
  pages={3390-7}
}
CONTEXT Thyroid nodules are common in adults, but only a small fraction of them is malignant. Fine-needle aspiration (FNA) cytology provides a definitive diagnosis of benign or malignant disease in many cases, whereas about 25% of nodules are indeterminate, hindering most appropriate management. OBJECTIVE The objective of the investigation was to study the clinical utility of molecular testing of thyroid FNA samples with indeterminate cytology. DESIGN Residual material from 1056 consecutive… CONTINUE READING
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The Bethesda System for Reporting Thyroid Cytopathology.

Thyroid : official journal of the American Thyroid Association • 2009
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Molecular diagnostics and predictors in thyroid cancer.

Thyroid : official journal of the American Thyroid Association • 2009

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