Impact of muscle biopsy on diagnosis and management of children with neuromuscular diseases: A 10-year retrospective critical review.

@article{Thavorntanaburt2018ImpactOM,
  title={Impact of muscle biopsy on diagnosis and management of children with neuromuscular diseases: A 10-year retrospective critical review.},
  author={Sivapol Thavorntanaburt and Jantima Tanboon and Surachai Likasitwattanakul and Tumtip Sangruchi and Ichizo Nishino and Monawat Ngerncham and Niramol Tantemsapya and Oranee Sanmaneechai},
  journal={Journal of pediatric surgery},
  year={2018},
  volume={53 3},
  pages={
          489-492
        }
}
BACKGROUND Muscle biopsy facilitates morphologic, biochemical, and ultrastructural analysis of muscle for the purpose of making definitive neuromuscular diagnosis. However, muscle biopsy is an expensive, invasive, time-consuming, and resource-dependent procedure. The need for general anesthesia in children also increases the risks associated with this procedure. The aim of this study was to investigate the benefits of muscle biopsies performed over a 10-year period, with a focus on indications… CONTINUE READING
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