Impact of matrix-assisted laser desorption ionization time-of-flight mass spectrometry on the clinical management of patients with Gram-negative bacteremia: a prospective observational study.

@article{Clerc2013ImpactOM,
  title={Impact of matrix-assisted laser desorption ionization time-of-flight mass spectrometry on the clinical management of patients with Gram-negative bacteremia: a prospective observational study.},
  author={Olivier Clerc and Guy Prod'hom and Christelle Vogne and Alain Bizzini and Thierry F Calandra and Gilbert Greub},
  journal={Clinical infectious diseases : an official publication of the Infectious Diseases Society of America},
  year={2013},
  volume={56 8},
  pages={1101-7}
}
BACKGROUND Early identification of pathogens from blood cultures using matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometry may optimize the choice of empirical antibiotic therapy in the setting of bloodstream infections. We aimed to assess the impact of this new technology on the use of antibiotic treatment in patients with gram-negative bacteremia. METHODS We conducted a prospective observational study from January to December 2010 to evaluate the… CONTINUE READING
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Direct identification of microorganisms in positive blood cultures using MALDI-TOF MS: consequences for advice on antibiotic therapy

  • CJ Hodiamont, T Gouliouris, W Rozemeijer
  • ECCMID
  • 2012
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