Impact of malaria on genetic polymorphism and genetic diseases in Africans and African Americans.

@article{Miller1994ImpactOM,
  title={Impact of malaria on genetic polymorphism and genetic diseases in Africans and African Americans.},
  author={Louis H. Miller},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1994},
  volume={91 7},
  pages={2415-9}
}
  • Louis H. Miller
  • Published 1994 in
    Proceedings of the National Academy of Sciences…
The high mortality from malaria in sub-Sahara Africa selected multiple genes that give the population a selective advantage. Identification of the genetic basis for resistance may suggest unusual approaches to development of malarial vaccines and antimalarial drugs. Some of these genes may be deleterious, although of selective advantage within the African setting, and need to be identified for counseling for disease prevention. 

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