Impact of intracytoplasmic sperm injection on the activation and fertilization process of oocytes.

@article{Ludwig2001ImpactOI,
  title={Impact of intracytoplasmic sperm injection on the activation and fertilization process of oocytes.},
  author={Michael A. Ludwig and Annika Schr{\"o}der and Klaus Diedrich},
  journal={Reproductive biomedicine online},
  year={2001},
  volume={3 3},
  pages={
          230-240
        }
}
Intracytoplasmic sperm injection (ICSI) is used worldwide to treat preferentially severe cases of male factor infertility. In this review, data regarding the processes of oocyte activation and fertilization in non-assisted conception, conventional IVF and ICSI are discussed. The second messenger calcium shows a typical pattern after ICSI, which is different from that after subzonal insemination (SUZI), which is closer to the conditions of normal fertilization. The onset of calcium spikes is… CONTINUE READING